Document Detail


The role of statins in deep vein thrombosis.
MedLine Citation:
PMID:  23272535     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Deep vein thrombosis (DVT) represents the formation of a blood clot in one of the deep veins of our body, predominantly occurring in the legs. According to international guidelines, the goal of the treatment in deep vein thrombosis is to prevent the progression and the recurrences of thrombotic process. The aim of this article is to explain the pathogenetic mechanism of deep vein thrombosis and the benefits of statins in such a disease. The vasoprotective effects of statins are related to their anti-thrombotic and anti-inflammatory properties. The administration of statins is associated with a lower incidence of venous thromboembolism (VTE) in the general population. It also helps in reducing the frequency of recurrences, being prescribed after an optimal 6 to 12 month anticoagulation. The study of these properties creates new opportunities for the use of statins in the prevention of post-thrombotic syndrome and recurrent venous thromboembolism (VTE).
Authors:
Maria-Magdalena Leon; Elena Cojocaru; Roxana Cobzaru; Amalia Didii; F Mitu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i     Volume:  116     ISSN:  0048-7848     ISO Abbreviation:  Rev Med Chir Soc Med Nat Iasi     Publication Date:    2012 Jul-Sep
Date Detail:
Created Date:  2012-12-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413735     Medline TA:  Rev Med Chir Soc Med Nat Iasi     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  817-22     Citation Subset:  IM    
Affiliation:
Discipline of Medical Semiology, University of Medicine and Pharmacy Grigore T. Popa-Iaşi School of Medicine.
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