Document Detail

The role of statins in acute coronary syndromes: managing the unmet need.
MedLine Citation:
PMID:  11070569     Owner:  NLM     Status:  MEDLINE    
Coronary heart disease is the major cause of death in the industrialised world. As the prevalence increases with advancing age, coronary heart disease will be a growing problem as the average age of the population increases. The cost of treatment following an acute coronary syndrome is considerable and there is a substantial risk of further episodes. However, there is much evidence that the disease is a dynamic and reversible process and further episodes are preventable. Numerous trials have shown the efficacy of statins in coronary heart disease. The most recent studies have shown efficacy in secondary prevention when statin therapy was started early (hours/days) after an acute episode. Although guidelines recommend that statin therapy should be initiated following an acute coronary syndrome, prescription rates seem to be static at around 40%. A number of measures need to be taken to improve the situation. Firstly, each hospital and coronary care unit should implement a clearly defined protocol delineating patient management following hospital admission. Provision of comprehensive discharge information should be a key feature of this communication. Secondly, regular audit of prescribing habits is essential to assess the situation. Finally, patient adherence to their regimen should be improved by collaborative involvement of doctor and patient in planning and implementing the treatment regimen.
G Jackson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of clinical practice     Volume:  54     ISSN:  1368-5031     ISO Abbreviation:  Int. J. Clin. Pract.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-11-20     Completed Date:  2000-11-20     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  9712381     Medline TA:  Int J Clin Pract     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  445-9     Citation Subset:  IM    
Cardiothoracic Centre, St Thomas' Hospital, London, UK.
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MeSH Terms
Anticholesteremic Agents / economics,  therapeutic use*
Clinical Protocols
Coronary Disease / drug therapy*,  economics
Cost-Benefit Analysis
Health Care Costs
Patient Compliance
Physician's Practice Patterns
Treatment Outcome
Reg. No./Substance:
0/Anticholesteremic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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