| The role of sonoelastography in acute, subacute and chronic thyroiditis - a novel application of the method. | |
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MedLine Citation:
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PMID: 22143319 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: Reports on sonoelastography, which provide an objective estimation of tissue elasticity, are scarce in terms of thyroiditis. The aim of the study was to prospectively assess the applicability of sonoelastography in different types of thyroiditis.Design: The study assessed and compared the thyroid tissue stiffness in patients with acute (AT), subacute (SAT) and chronic thyroiditis (CAT) with healthy controls (CS), followed-up for 10 weeks.Methods: The studied group consisted of two patients with AT, 18 patients with SAT, 18 patients with CAT and a 40 CS, matched for age and gender. Sonoelastography was performed: at baseline, at a 4-week follow-up during treatment, and 10 weeks following diagnosis and treatment initiation.Results: Thyroid tissue stiffness was higher in SAT at baseline (214.26±32.5kPa) in comparison to values recorded at a 4-week follow-up (45.92±17.4kPa) and 21.65±5.3kPa 10 weeks following diagnosis and treatment initiation (p<0.0001). Baseline thyroid stiffness in SAT was higher than that found in CAT (36.15±18.7kPa, p<0.0001) and CS (16.18±5.4kPa, p<0.0001). In the remission of SAT, thyroid stiffness was lower than that found in CAT (p=0.006), while higher than in CS (p=0.0008). No difference was observed between thyroid stiffness in SAT at 4-week follow-up and in CAT. Patients with CAT presented higher thyroid stiffness than CS (p<0.0001) which was not influenced by L-thyroxine treatment. Thyroid stiffness in patients with AT was 216.6kPa and 241.9kPa at baseline; after treatment it decreased to 17.93kPa and 85.348kPa, respectively.Conclusions: Sonoelastography may assist in the diagnosis and treatment monitoring of AT, SAT and CAT, as well as in the differentiation of the various types of thyroiditis. |
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Authors:
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Marek Ruchala; Ewelina Szczepanek-Parulska; Ariadna Zybek; Jerzy Moczko; Agata Czarnywojtek; Grzegorz Kaminski; Jerzy Sowinski |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-5 |
Journal Detail:
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Title: European journal of endocrinology / European Federation of Endocrine Societies Volume: - ISSN: 1479-683X ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9423848 Medline TA: Eur J Endocrinol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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M Ruchala, Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan, 60-355, Poland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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