Document Detail

The role of single serum progesterone measurement in conjunction with beta hCG in the management of suspected ectopic pregnancy.
MedLine Citation:
PMID:  18604677     Owner:  NLM     Status:  MEDLINE    
Our aim was to test the use of single serum progesterone measurement together with beta hCG in the management of women with pregnancy of unknown location. This was a retrospective study of 126 patients presenting with a clinical picture suggestive of ectopic pregnancy, when ultrasound examination was inconclusive. All the patients had serum progesterone level measured by radioimmunoassay in conjunction with beta hCG. The study showed that a protocol combining single serum progesterone measurement and beta hCG is helpful in managing women with suspected ectopic pregnancies, when the ultrasound examination is inconclusive. High levels of progesterone are reassuring as regards ongoing viable pregnancies and low levels allow a definitive differentiation between viable and non-viable pregnancies. However, low progesterone could not efficiently differentiate between miscarriage and ectopic pregnancy. The use of beta hCG levels in conjunction with serum progesterone is helpful, particularly with serum progesterone levels between 16-80 nmol/l.
G El Bishry; S Ganta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  28     ISSN:  1364-6893     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-07-08     Completed Date:  2008-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  413-7     Citation Subset:  IM    
University Hospital of North Durham, UK.
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MeSH Terms
Abortion, Spontaneous / diagnosis
Biological Markers / blood
Chorionic Gonadotropin, beta Subunit, Human / blood*
Diagnosis, Differential
Pregnancy, Ectopic / diagnosis*
Progesterone / blood*
Sensitivity and Specificity
Reg. No./Substance:
0/Biological Markers; 0/Chorionic Gonadotropin, beta Subunit, Human; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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