| The role of sclerotherapy as an adjunct to Unna's boot for treating venous ulcers: a prospective study. | |
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MedLine Citation:
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PMID: 2325217 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ankle ulcers associated with venous disease have been traditionally treated by Unna's compressive bandages. However, successful healing of an ulcer with this therapeutic modality is slow and tedious. The purpose of this study is to investigate whether adjunctive sclerotherapy of large venous channels near the ulcers enhances healing. Twenty-eight patients with perimalleolar venous ulceration were entered into this study. Ulcer size ranged from 6.0 to 25 cm2. All were examined for the presence of large venous channels adjacent to the ulcer bed. A portable continuous-wave Doppler supplemented digital examination of the area. Twenty-five out of 28 patients had easily detectable venous channels, and these were randomized into two groups: group I, treated by weekly changes of Unna's compressive boots; group II, treated by weekly change of Unna's compressive boots and sclerotherapy with 3% sodium tetradecyl sulfate (Sotradecol). All patients had the size of the ulcer measured during their weekly visits. Patients in group II took a mean of 2.1 weeks to exhibit 50% healing and 4.3 weeks to fully heal. Conversely patients in group I took a mean of 3.2 weeks to achieve 50% healing and 6.1 weeks to fully heal. Thus, healing was significantly faster (p less than 0.05) in group II. In conclusion, the therapeutic efficiency of Unna's compressive bandaging is significantly enhanced by the adjunctive sclerotherapy of adjacent venous channels. |
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Authors:
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L A Queral; F J Criado; M P Lilly; D Rudolphi |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of vascular surgery Volume: 11 ISSN: 0741-5214 ISO Abbreviation: J. Vasc. Surg. Publication Date: 1990 Apr |
Date Detail:
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Created Date: 1990-05-16 Completed Date: 1990-05-16 Revised Date: 2012-10-03 |
Medline Journal Info:
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Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 572-5 Citation Subset: IM |
Affiliation:
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Maryland Vascular Institute, Baltimore 21218. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Bandages* Chronic Disease Combined Modality Therapy Humans Middle Aged Pressure Prognosis Prospective Studies Sclerotherapy* Varicose Ulcer / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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