Document Detail


The role of the right ventricle in pulmonary arterial hypertension.
MedLine Citation:
PMID:  22130817     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Although changes in the pulmonary vasculature are the primary cause of pulmonary arterial hypertension (PAH), severity of symptoms and survival are strongly associated with right ventricular function, and right heart failure is the main cause of death in patients with PAH. Echocardiography and cardiac magnetic resonance imaging allow noninvasive evaluation of right ventricular function and structure, and a number of indices have been shown to have potential prognostic value in PAH. Given the importance of the right ventricle in PAH, preservation and improvement of its function should be important aspects of therapy; however, there are currently few data specifically related to this aspect of treatment response. Simple, reproducible, noninvasive measures of right ventricular function would help to improve the management of patients with PAH, and to provide tools with which to help establish the optimal therapeutic approach to manage not only the effects of the disease on the pulmonary vasculature, but also to support and improve right ventricular function.
Authors:
A Vonk Noordegraaf; N Galiè
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European respiratory review : an official journal of the European Respiratory Society     Volume:  20     ISSN:  1600-0617     ISO Abbreviation:  Eur Respir Rev     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111391     Medline TA:  Eur Respir Rev     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  243-53     Citation Subset:  IM    
Affiliation:
VU University Medical Center, Amsterdam, The Netherlands. # University of Bologna, Bologna, Italy.
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