Document Detail

The role of renin substrate in hypertension.
MedLine Citation:
PMID:  6341219     Owner:  NLM     Status:  MEDLINE    
A positive correlation between blood pressure and renin substrate concentration is found in a wide variety of conditions in human beings and in animal experiments. The evidence concerning this relationship is reviewed and the exceptions are discussed. The frequent positive correlation between renin substrate and elevated blood pressure suggests that increased renin substrate concentration may be a causal factor in hypertension.
D B Gordon
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Hypertension     Volume:  5     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:    1983 May-Jun
Date Detail:
Created Date:  1983-06-17     Completed Date:  1983-06-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  353-62     Citation Subset:  IM    
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MeSH Terms
Angiotensinogen / physiology*
Angiotensins / physiology*
Bartter Syndrome / physiopathology
Blood Pressure
Contraceptives, Oral / pharmacology
Cushing Syndrome / physiopathology
Diethylstilbestrol / therapeutic use
Diuretics / therapeutic use
Estrogens / pharmacology
Hypertension / blood,  drug therapy,  physiopathology*
Hypotension / physiopathology
Liver / injuries
Liver Cirrhosis / physiopathology
Middle Aged
Pregnancy Complications, Cardiovascular / physiopathology
Prostatic Neoplasms / drug therapy
Renin / blood
Vascular Resistance / drug effects
Reg. No./Substance:
0/Angiotensins; 0/Contraceptives, Oral; 0/Diuretics; 0/Estrogens; 11002-13-4/Angiotensinogen; 56-53-1/Diethylstilbestrol; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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