| The role of renal resistive index measures in the diagnostic work up of congenital hydronephrosis. | |
| | |
MedLine Citation:
|
PMID: 18947629 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the role of renal resistive index (RI) measures in the diagnostic work up of congenital hydronephrosis. METHODS AND MATERIALS: Seventeen neonatal pigs were randomized to either left-sided partial unilateral ureteral obstruction (n=12) or sham operation (n=5) at 2weeks of age. Serial investigations including B-mode ultrasound, RI measures and combined clearance/renographic evaluations were performed at 4, 12 and 24weeks of age under light sedation. Results were analysed statistically, and receiver operating characteristic (ROC) curves were generated in order to evaluate the diagnostic efficacy of RI. RESULTS: In all, 15 animals completed the study protocol. In the obstructed group, hydronephrosis and significant compromise of renal function developed on the subject side, whereas sham-operated pigs had stable renal morphology and function throughout the study. There were however no significant differences in RI or DeltaRI between the two groups at any age, or between right and left RIs in the obstructed group at any point. RI and DeltaRI had no prognostic or diagnostic value as judged by ROC curve analysis. CONCLUSIONS: RI and DeltaRI were not affected by partial unilateral ureteral obstruction induced in the immature neonatal porcine kidney. The results of this study do not support the clinical use of Doppler ultrasound studies in the diagnostic work up of congenital hydronephrosis. |
| | |
Authors:
|
Yazan F Rawashdeh; Arne Hørlyck; Jens Mortensen; Jorgen Frokiaer; Jens C Djurhuus |
Related Documents
:
|
3047469 - Prevalence of fatty liver in a general population of okinawa, japan. 9831349 - X-inactivation pattern in the liver of a manifesting female with ornithine transcarbamy... 20502969 - The hydrogen sulfide signaling system: changes during aging and the benefits of caloric... 6727439 - Influence of age-related changes in rodent liver morphology and physiology on drug meta... 6499359 - Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in b... 17216989 - Ultra sonographic measurements of the normal liver and spleen among egyptians 10-50 yea... 6729439 - Concentrations of four essential trace elements in breast milk of mothers from two soci... 21987489 - Age-related regional brain t2-relaxation changes in healthy adults. 21368449 - Oxidised low-density lipoprotein concentrations and physical activity status in older a... |
Publication Detail:
|
Type: Journal Article Date: 2006-03-31 |
Journal Detail:
|
Title: Journal of pediatric urology Volume: 2 ISSN: 1873-4898 ISO Abbreviation: - Publication Date: 2006 Aug |
Date Detail:
|
Created Date: 2008-10-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101233150 Medline TA: J Pediatr Urol Country: England |
Other Details:
|
Languages: eng Pagination: 316-22 Citation Subset: - |
Affiliation:
|
Department of Urology, Institute of Clinical Medicine, Aarhus University Hospital, Skejby, 8200 Aarhus N, Denmark. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dysfunctional elimination syndrome is a negative predictor for vesicoureteral reflux.
Next Document: A case series of nephrogenic adenoma of the urethra and bladder in children: Review of this rare dia...