Document Detail


The role of reduced left ventricular enddiastolic volume in the apparently high prevalence of mitral valve prolapse in atrial septal defect.
MedLine Citation:
PMID:  7398725     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-three patients with ostium-secundum atrial septal defect (ASD) were studied in order to investigate the etiology of angiographic mitral valve prolapse associated with ostium-secundum ASD. 12 patients (52%) had angiograhic MVP. Ventricular volumes, ejection fraction, segmentary contractility and oxygen step-up were analyzed in all patients. Patients with MVP had smaller enddiastolic and stroke volumes (73 +/- 21.8 ml/m2 and 46.6 +/- 18 ml/beat/m2) than patients without MVP (106.6 +/- 22 ml/m2 and 78 +/- 11.3 ml/beat/m2) (P less than 0.01). Oxygen step-up was greater in patients with MVP (P less than 0.05). No consistent differences in ejection fraction and segmentary contractility were found. Our findings suggest that angiographic MVP associated with ostium-secundum ASD is a functional disorder due to reduced left ventricular enddiastolic volume secondary to the atrial shunt.
Authors:
J Angel; J Soler-Soler; H Garcia del Castillo; I Anivarro; J Batlle-Diaz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiology     Volume:  11     ISSN:  0301-4711     ISO Abbreviation:  Eur J Cardiol     Publication Date:  1980  
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404054     Medline TA:  Eur J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  341-55     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cardiac Volume*
Child
Diastole
Female
Heart Septal Defects, Atrial / complications*,  physiopathology
Humans
Male
Middle Aged
Mitral Valve Prolapse / complications*,  etiology,  physiopathology
Myocardial Contraction
Oxygen / blood
Stroke Volume
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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