| The role of reduced left ventricular enddiastolic volume in the apparently high prevalence of mitral valve prolapse in atrial septal defect. | |
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MedLine Citation:
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PMID: 7398725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-three patients with ostium-secundum atrial septal defect (ASD) were studied in order to investigate the etiology of angiographic mitral valve prolapse associated with ostium-secundum ASD. 12 patients (52%) had angiograhic MVP. Ventricular volumes, ejection fraction, segmentary contractility and oxygen step-up were analyzed in all patients. Patients with MVP had smaller enddiastolic and stroke volumes (73 +/- 21.8 ml/m2 and 46.6 +/- 18 ml/beat/m2) than patients without MVP (106.6 +/- 22 ml/m2 and 78 +/- 11.3 ml/beat/m2) (P less than 0.01). Oxygen step-up was greater in patients with MVP (P less than 0.05). No consistent differences in ejection fraction and segmentary contractility were found. Our findings suggest that angiographic MVP associated with ostium-secundum ASD is a functional disorder due to reduced left ventricular enddiastolic volume secondary to the atrial shunt. |
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Authors:
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J Angel; J Soler-Soler; H Garcia del Castillo; I Anivarro; J Batlle-Diaz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of cardiology Volume: 11 ISSN: 0301-4711 ISO Abbreviation: Eur J Cardiol Publication Date: 1980 |
Date Detail:
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Created Date: 1980-10-27 Completed Date: 1980-10-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404054 Medline TA: Eur J Cardiol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 341-55 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cardiac Volume* Child Diastole Female Heart Septal Defects, Atrial / complications*, physiopathology Humans Male Middle Aged Mitral Valve Prolapse / complications*, etiology, physiopathology Myocardial Contraction Oxygen / blood Stroke Volume |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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