| The role of proton pump inhibitors in the treatment of heartburn during pregnancy. | |
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MedLine Citation:
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PMID: 15679877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To review the problem of heartburn in gravid women, discuss the present treatment options, and examine the use of proton pump inhibitors (PPIs) as one of the treatment options for moderate to severe heartburn. DATA SOURCES: Extensive review of worldwide scientific literature on the use and safety of PPIs during pregnancy and heartburn during pregnancy. CONCLUSIONS: Preliminary information indicates that use of PPIs during pregnancy is safe for both the fetus and the woman and that obstetrical practitioners are using them more frequently. Randomized controlled trials are needed to examine the efficacy of PPIs to treat heartburn during pregnancy, especially as they are compared to histamine(2) receptor antagonists. IMPLICATIONS FOR PRACTICE: Heartburn during pregnancy is at risk for being undertreated, given that delivery is the cure. As PPIs are more widely used by women, questions will arise regarding their use in the first trimester as well as throughout pregnancy. This article brings nurse practitioners up to date on the safety of PPIs through the literature review and suggests various treatment options that can be discussed with the patient. |
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Authors:
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Lesliea Christopher |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of the American Academy of Nurse Practitioners Volume: 17 ISSN: 1041-2972 ISO Abbreviation: J Am Acad Nurse Pract Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-01-31 Completed Date: 2005-06-28 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8916634 Medline TA: J Am Acad Nurse Pract Country: United States |
Other Details:
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Languages: eng Pagination: 4-8 Citation Subset: N |
Affiliation:
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leslie.christopher@lackland.af.mil |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Ulcer Agents
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therapeutic use* Female Heartburn / complications, drug therapy* Humans Pregnancy Pregnancy Complications / drug therapy* Proton Pumps / antagonists & inhibitors* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Ulcer Agents; 0/Proton Pumps |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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