| The role of proteases during apoptosis. | |
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MedLine Citation:
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PMID: 8621058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The importance of proteases during apoptosis is becoming increasingly apparent. Because apoptosis contributes to a diverse variety of disease processes, understanding the roles played by proteases and their inhibitors might provide insight into the pathogenesis of these conditions and suggest novel therapeutic strategies. In this review, we discuss the involvement and role of specific proteases, substrates, and protease inhibitors that appear to participate in the apoptotic process. |
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Authors:
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T Patel; G J Gores; S H Kaufmann |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: FASEB journal : official publication of the Federation of American Societies for Experimental Biology Volume: 10 ISSN: 0892-6638 ISO Abbreviation: FASEB J. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-06-19 Completed Date: 1996-06-19 Revised Date: 2012-02-15 |
Medline Journal Info:
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Nlm Unique ID: 8804484 Medline TA: FASEB J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 587-97 Citation Subset: IM |
Affiliation:
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Center for Basic Research in Digestive Diseases, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Apoptosis / physiology* Caspase 1 Cysteine Endopeptidases / metabolism Endopeptidases / metabolism* Humans Lamins Nuclear Proteins / metabolism Poly(ADP-ribose) Polymerases / metabolism Protease Inhibitors / metabolism Ribonucleoproteins, Small Nuclear / metabolism |
| Grant Support | |
ID/Acronym/Agency:
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CA69008/CA/NCI NIH HHS; DK14876/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Lamins; 0/Nuclear Proteins; 0/Protease Inhibitors; 0/Ribonucleoproteins, Small Nuclear; EC 2.4.2.30/Poly(ADP-ribose) Polymerases; EC 3.4.-/Endopeptidases; EC 3.4.22.-/Cysteine Endopeptidases; EC 3.4.22.36/Caspase 1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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