| The role of prophylactic antibiotics in middle ear surgery. A study on phenoxymethylpenicillin prophylaxis. | |
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MedLine Citation:
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PMID: 3124628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A randomized prospective double-blind study was performed testing the value of phenoxymethylpenicillin in conjunction with middle ear surgery. The patients were evaluated for clinical signs of infection and with bacteriologic cultures both pre- and postoperatively. No difference in clinical signs of infection was noted between the pre- and postoperative evaluations. A significantly larger number of patients, however, presented with postoperative positive bacteriologic cultures as compared with the preoperative cultures. This increase was particularly evident in the placebo group. The two microorganisms that were found in increased numbers postoperatively were Staphylococcus epidermidis and Pseudomonas strains. The value of prophylactic antibiotic treatment and phenoxymethylpenicillin treatment in particular is discussed. |
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Authors:
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D Bagger-Sjöbäck; L Mendel; C E Nord |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The American journal of otology Volume: 8 ISSN: 0192-9763 ISO Abbreviation: Am J Otol Publication Date: 1987 Nov |
Date Detail:
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Created Date: 1988-02-26 Completed Date: 1988-02-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7909513 Medline TA: Am J Otol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 519-23 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bacteria / isolation & purification Clinical Trials as Topic Double-Blind Method Ear, Middle / microbiology, surgery* Humans Penicillin V / therapeutic use* Premedication* Random Allocation |
| Chemical | |
Reg. No./Substance:
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87-08-1/Penicillin V |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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