Document Detail

The role of preparatory cycles in ovum donation recipients: a retrospective study.
MedLine Citation:
PMID:  15672949     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine whether preparatory cycles affect in vitro fertilization (IVF) outcome in ovum donation.
METHODS: Medical records of 98 ovum donation recipients undergoing their first egg donation cycle were analyzed retrospectively. Preparatory cycles were performed in 50 patients with leuprolide acetate, estrogen, and progesterone. An endometrial biopsy was performed on day 10-12 of progesterone supplementation, to determine adequacy of the preparatory cycle.
RESULTS: Pregnancy rates in women with and without preparatory cycles were 42.0% and 43.8%, respectively. Among ovum donation recipients who underwent preparatory cycles, the percentages of adequate endometrial biopsies in pregnant versus nonpregnant groups were 76.2% and 84.3%, respectively. No results showed statistical significance.
CONCLUSIONS: Preparatory cycles do not increase pregnancy rates in ovum donation recipients. In addition, no correlation was noted between adequate endometrial biopsies and higher pregnancy rates.
Sunny H Jun; Catherine Racowsky; Janis H Fox; Mark D Hornstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  21     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2005-01-27     Completed Date:  2005-05-03     Revised Date:  2013-03-26    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  377-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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MeSH Terms
Aging / physiology
Embryo Transfer*
Endometrium / physiology
Estrogens / pharmacology
Fertilization in Vitro
Infertility, Female / therapy*
Oocyte Donation*
Ovary / physiology*
Pregnancy Outcome
Pregnancy Rate
Progesterone / pharmacology
Retrospective Studies
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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