| The role of positron emission tomography/computed tomography in the diagnosis of pleural diseases. | |
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MedLine Citation:
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PMID: 19670115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aim of the study was to assess the role of F-18 fluoro-2-D-deoxyglucose positron emission tomography ( (18)FDG-PET)/computed tomography (CT) in patients with undiagnosed pleural diseases and to compare the findings with those of invasive diagnostic procedures. METHODS: The study included 83 patients with pleural lesions (63 with pleural effusion; 20 with pleural thickening) on CT scan performed between November 2005 and December 2007. The study group consisted of 63 males and 20 females; their median age was 47 years. PET-CT scan was performed for all patients before surgery. A maximum standard uptake value greater than 3.0 was accepted as positive for malignancy. For histopathological diagnosis, video-assisted thoracoscopic surgery was performed in 76 patients and a mini-thoracotomy was performed for the remaining 7 patients. RESULTS: Postoperative histopathological examination revealed malignancy in 44 cases, 25 of which were malignant mesothelioma; the remaining 39 cases were benign. There were no false negative results, but two false positive results (tuberculosis). PET-CT scanning had 100 % sensitivity, 94.8 % specificity and 97.5 % accuracy. CONCLUSION: Our study suggests that PET-CT may be an effective tool for the differentiation of benign and malignant pleural diseases. We believe that PET/CT may prevent redundant surgical procedures in young patients who are SUVmax negative. |
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Authors:
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A Orki; O Akin; A E Tasci; H Ciftci; S Urek; O Falay; C A Kutlu |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-05-20 |
Journal Detail:
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Title: The Thoracic and cardiovascular surgeon Volume: 57 ISSN: 1439-1902 ISO Abbreviation: Thorac Cardiovasc Surg Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-08-11 Completed Date: 2009-10-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7903387 Medline TA: Thorac Cardiovasc Surg Country: Germany |
Other Details:
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Languages: eng Pagination: 217-21 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart New York. |
Affiliation:
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Thoracic Surgery, Maltepe University School of Medicine, Istanbul, Turkey. alpayorki@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diagnosis, Differential False Positive Reactions Female Fluorodeoxyglucose F18 / diagnostic use Humans Male Mesothelioma / diagnosis, pathology Middle Aged Pleural Diseases / diagnosis* Pleural Effusion / diagnosis, pathology Pleural Neoplasms / diagnosis Positron-Emission Tomography* Radiopharmaceuticals / diagnostic use Sensitivity and Specificity Thoracic Surgery, Video-Assisted Thoracotomy Tomography, X-Ray Computed* Tuberculosis, Pleural / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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