Document Detail

The role of peritoneal dialysis in the treatment of ascites.
MedLine Citation:
PMID:  22130279     Owner:  NLM     Status:  MEDLINE    
Cirrhosis represents a late stage of hepatic fibrosis and leads to high morbidity and mortality, and the most frequent complication is ascites. Only a few patients with advanced cirrhosis have 'refractory ascites' and do not respond to conventional treatment. Repeated paracentesis for evacuation is considered the treatment of choice in these cases. A large proportion of these patients have associated chronic kidney disease (CKD), which may require renal replacement therapy (RRT). Due to the complications associated with liver disease with coagulation disorders and tendencies towards spontaneous hypotension, there are significant problems associated to RRT, especially haemodialysis (HD). On the contrary, peritoneal dialysis (PD) offers several advantages over HD in cirrhotic patients (with or without ascites) thanks to better haemodynamic tolerance, as it is a continuous and slow technique. Furthermore, PD has a low rate of infection and bleeding.
S Ros Ruiz; E Gutiérrez Vilchez; T P García Frías; T M Martín Velázquez; L Blanca Martos; T Jiménez Salcedo; D Hernández Marrero
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nefrología : publicación oficial de la Sociedad Española Nefrologia     Volume:  31     ISSN:  1989-2284     ISO Abbreviation:  Nefrologia     Publication Date:  2011  
Date Detail:
Created Date:  2011-12-01     Completed Date:  2012-04-24     Revised Date:  2012-08-20    
Medline Journal Info:
Nlm Unique ID:  8301215     Medline TA:  Nefrologia     Country:  Spain    
Other Details:
Languages:  eng; spa     Pagination:  648-55     Citation Subset:  IM    
Unidad de Nefrología, Hospital Regional Carlos Haya, Playa Park 2, Málaga, Spain.
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MeSH Terms
Ascites / etiology,  physiopathology,  therapy*
Blood Coagulation Disorders / etiology
Chronic Disease
Hepatitis, Viral, Human / epidemiology,  etiology,  transmission
Hypoproteinemia / etiology
Hypotension / etiology
Kidney Diseases / complications,  therapy
Liver Cirrhosis / complications
Malnutrition / etiology
Peritoneal Dialysis* / adverse effects,  methods
Peritonitis / etiology
Renal Dialysis / adverse effects
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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