| The role of omentectomy during the surgical staging in patients with clinical stage I endometrioid adenocarcinoma. | |
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MedLine Citation:
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PMID: 18386056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to evaluate whether omentectomy should be a routine part of staging surgery in endometrioid adenocarcinoma. METHODS: A retrospective study was performed on 65 patients who were primarily treated by total abdominal hysterectomy, salpingo-oophorectomy, bilateral pelvic and para-aortic lymphadenectomy, infracolic omentectomy and peritoneal cytology for clinical stage I endometrial carcinoma between January 2002 and December 2005. Data on 65 patients who had been diagnosed with clinical stage I endometrial carcinoma were reviewed. Associations in the data obtained, pelvic and para-aortic lymph node status, depth of myometrial invasion, grade, vascular invasion, adnexal involvement, positive peritoneal cytology, lymph node metastasis, cervical stromal invasion, and tumor size, were investigated. The Chi-square (chi(2)) test was used for statistical analysis. Multivariate analysis was performed with logistic regression analyses. RESULTS: Four (6.2%) of 65 patients had omental metastasis, which was microscopic in two patients. As for extrauterine spread, the positivity rate of lymph node metastases was 10/65 (15.38%), peritoneal cytology was 7/65 (10.76%), and adnexal metastases was 10/65 (15.38%). Of those patients with omental metastasis, 2/10(20%) had positive nodes, 2/10(20%) had adnexal metastases, and 3/7(42.8%) had positive peritoneal cytologic findings. These four patients with omental metastasis had significantly higher rates of positive cytology (P = 0.003). Multivariate analysis revealed omental metastasis (P = 0.002; OR 46.5, CI 95% 3.899-554.575) to be significantly associated with positive peritoneal cytology CONCLUSIONS: We conclude that despite the presence of normal-appearing omentum, omentectomy should be performed as a component of surgical staging in the presence of positive peritoneal cytology. |
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Authors:
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Jale Metindir; Gülay Bilir Dilek |
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Publication Detail:
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Type: Journal Article Date: 2008-04-02 |
Journal Detail:
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Title: Journal of cancer research and clinical oncology Volume: 134 ISSN: 0171-5216 ISO Abbreviation: J. Cancer Res. Clin. Oncol. Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-08-21 Completed Date: 2008-12-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902060 Medline TA: J Cancer Res Clin Oncol Country: Germany |
Other Details:
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Languages: eng Pagination: 1067-70 Citation Subset: IM |
Affiliation:
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Department of Gynecology, Ankara Oncology Education and Research Hospital, Ahmet Mithat Efendi Sok No: 58/11, Cankaya/Ankara, Turkey. jmetindir@ttmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Endometrioid / pathology*, surgery* Female Genital Neoplasms, Female / pathology*, surgery* Gynecologic Surgical Procedures Humans Middle Aged Neoplasm Staging / methods Omentum / pathology*, surgery* Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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