Document Detail

The role of oestrogen replacement in the climacteric syndrome.
MedLine Citation:
PMID:  201958     Owner:  NLM     Status:  MEDLINE    
Using a double-blind placebo-controlled cross-over design, the effect of equine conjugated oestrogens tablets (Premarin) was studied in 20 women with the climacteric syndrome followed during 15 months. Sixteen women were equally improved on placebo and oestrogen. Only 2 patients had an improved sense of well-being on oestrogen and not on placebo. The psychological diagnosis was unrelated to the subjective response to oestrogen or placebo. Performance in psychological tests administered before and during treatment periods was not changed by oestrogen or placebo.
R C Strickler; R Borth; A Cecutti; B A Cookson; J A Harper; R Potvin; P Riffel; V J Sorbara; C A Woolever
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Psychological medicine     Volume:  7     ISSN:  0033-2917     ISO Abbreviation:  Psychol Med     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1254142     Medline TA:  Psychol Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  631-9     Citation Subset:  IM    
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MeSH Terms
Attitude of Health Personnel
Climacteric / drug effects*
Cornell Medical Index
Depression / drug therapy
Double-Blind Method
Drug Evaluation
Emotions / drug effects
Estrogens, Conjugated (USP) / therapeutic use*
Middle Aged
Personality Tests
Professional-Patient Relations
Reg. No./Substance:
0/Estrogens, Conjugated (USP); 0/Placebos

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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