Document Detail


The role of nutritional modifications in the prevention of macrovascular complications of diabetes.
MedLine Citation:
PMID:  9285514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A wide range of dietary changes is likely to reduce the risk of macrovascular complications of diabetes. It is critically important to recommend a balance of macronutrients different from that currently consumed in most Western countries. Saturated fatty acids, especially myristic and palmitic acids, and trans fatty acids must be reduced to lower LDL cholesterol. Intake of polyunsaturated fatty acids should not be excessive (less than 10% total energy). Fiber-rich carbohydrate, derived from cereals, vegetables, and fruit with intact cell walls, and cis monounsaturated fatty acids should provide the bulk of total energy. These changes are likely to be associated with the most favorable lipoprotein profile and increase intake of dietary antioxidants and so reduce the level of oxidative stress. A reduction of sodium to below 6 g per day will help to reduce blood pressure levels. Optimal glycemic control has not yet been proved to reduce the risk of macrovascular complications, though this is a desirable goal for many other reasons. Ensuring appropriate energy balance (so that BMI is within the desirable range), using low glycemic index foods, and appropriately balancing carbohydrate intake with hypoglycemic drug therapy provide the best nutritional means of achieving satisfactory blood glucose levels. Successful implementation of nutritional recommendations requires the availability of dietitians capable of translating appropriate nutrition into appropriate foods acceptable to people with diabetes and their families. Clear food labeling and the availability of appropriate manufactured foods will further help patients with diabetes to achieve the dietary recommendations.
Authors:
J I Mann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diabetes     Volume:  46 Suppl 2     ISSN:  0012-1797     ISO Abbreviation:  Diabetes     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-09-25     Completed Date:  1997-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372763     Medline TA:  Diabetes     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S125-30     Citation Subset:  AIM; IM    
Affiliation:
Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / therapeutic use
Body Mass Index
Cardiovascular Diseases / prevention & control
Cholesterol / metabolism
Diabetes Mellitus, Type 1 / complications,  metabolism,  therapy*
Diabetic Angiopathies / prevention & control*
Diet Therapy
Energy Intake
Energy Metabolism
Humans
Lovastatin / analogs & derivatives,  therapeutic use
Minerals / metabolism
Obesity / complications
Simvastatin
Vitamins / metabolism
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Minerals; 0/Vitamins; 57-88-5/Cholesterol; 75330-75-5/Lovastatin; 79902-63-9/Simvastatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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