Document Detail

The role of the nucleus pulposus in neutral zone human lumbar intervertebral disc mechanics.
MedLine Citation:
PMID:  18571654     Owner:  NLM     Status:  MEDLINE    
To study the effect of denucleation on the mechanical behavior of the human lumbar intervertebral disc through a 2mm incision, two groups of six human cadaver lumbar spinal units were tested in axial compression, axial rotation, lateral bending and flexion/extension after incremental steps of "partial" denucleation. Neutral zone, range of motion, stiffness, intradiscal pressure and energy dissipation were measured; the results showed that the contribution of the nucleus pulposus to the mechanical behavior of the intervertebral disc was more dominant through the neutral zone than at the farther limits of applied loads and moments.
Marco Cannella; Amy Arthur; Shanee Allen; Michael Keane; Abhijeet Joshi; Edward Vresilovic; Michele Marcolongo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-06-20
Journal Detail:
Title:  Journal of biomechanics     Volume:  41     ISSN:  0021-9290     ISO Abbreviation:  J Biomech     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-07-15     Completed Date:  2008-09-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2104-11     Citation Subset:  IM    
Department of Materials Science and Engineering, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.
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MeSH Terms
Biomechanics / methods*
Equipment Design
Intervertebral Disk / anatomy & histology*
Lumbar Vertebrae / anatomy & histology*
Lumbosacral Region / anatomy & histology
Range of Motion, Articular
Stress, Mechanical
Tensile Strength
Zygapophyseal Joint / anatomy & histology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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