Document Detail

The role of nuclear medicine in the management of Graves' disease.
MedLine Citation:
PMID:  10731780     Owner:  NLM     Status:  MEDLINE    
131I therapy is safe and effective for most Graves' disease patients. It is being used more frequently in previously restricted populations such as children, adolescents, and women of childbearing age. It affords prompt, consistent relief of hyperthyroidism, but permanent hypothyroidism ensues in almost all patients. This complication is readily diagnosed with modern in vitro assays and inexpensive, life-long replacement therapy renders the patient asymptomatic and able to resume a normal lifestyle. Recent changes in NRC requirements have further liberalized the use of 131I for Graves' disease in the USA, permitting more patients to be treated with effective outpatient therapy. The controversial role of 131I in exacerbation of GO has been further clarified and preventive measures are available.
J E Freitas
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR)     Volume:  43     ISSN:  1125-0135     ISO Abbreviation:  Q J Nucl Med     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-04-05     Completed Date:  2000-04-05     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9512274     Medline TA:  Q J Nucl Med     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  297-306     Citation Subset:  IM    
Nuclear Medicine Services, St. Joseph Mercy Hospital, Ann Arbor, MI 48106-0995, USA.
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MeSH Terms
Graves Disease / diagnosis,  radiotherapy*
Hypothyroidism / etiology
Iodine Radioisotopes / adverse effects,  therapeutic use*
Radiotherapy Dosage
Risk Factors
Reg. No./Substance:
0/Iodine Radioisotopes

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