Document Detail


The role of neuropeptide y in energy homeostasis.
MedLine Citation:
PMID:  22249809     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
When administered into the brain, NPY acts at Y1 and Y5 receptors to increase food intake. The response occurs with a short latency and is quite robust, such that exogenous NPY is generally considered to be the most potent of a growing list of orexigenic compounds that act in the brain. The role of endogenous NPY is not so straightforward, however. Evidence from diverse types of experiments suggests that rather than initiating behavioral eating per se, endogenous NPY elicits autonomic responses that prepare the individual to better cope with consuming a calorically large meal.
Authors:
Adam P Chambers; Stephen C Woods
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Handbook of experimental pharmacology     Volume:  209     ISSN:  0171-2004     ISO Abbreviation:  Handb Exp Pharmacol     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902231     Medline TA:  Handb Exp Pharmacol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  23-45     Citation Subset:  IM    
Affiliation:
Departments of Medicine, University of Cincinnati, 2170 East Galbraith Road, Cincinnati, OH, 45237, USA.
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