Document Detail

The role of myocardial perfusion imaging in the evaluation of patients undergoing percutaneous transluminal coronary angioplasty.
MedLine Citation:
PMID:  19767281     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: We studied the value of myocardial perfusion imaging (MPI) for the evaluation of improvement in myocardial perfusion in patients with successful percutaneous transluminal coronary angioplasty (PTCA).
METHODS: Sixty patients (10 women, 50 men) aged 54.18 +/- 11.71 years were analyzed. MPI was performed before PTCA, 6-10 days (16 cases), 1-3 months (21 cases), and then 3-6 months (23 cases) after the procedure. In all patients repeated coronary angiography was done at least once after PTCA. Statistical analysis of the numbers of segments with various degrees of perfusion (normal, ischemia, fixed segment), before and after PTCA, was performed for three groups (6-10 days, 1-3 months and 3-6 months after PTCA) separately, using paired T and also ANOVA tests. A p-value <0.05 was considered to be statistically significant.
RESULTS: Improvement, defined as a decrease in the number of ischemic or fixed segments, was observed in 13 of 16 patients at 6-10 days after PTCA, in 18 of 21 cases 1-3 months after PTCA, and in 20 of 23 patients 3-6 months after PTCA. The sensitivity and specificity of MPI calculated before PTCA and at the 3 subsequent time points, using angiography as the gold standard, were 80/81, 100/35, 90/100, and 76/100 percent, respectively.
CONCLUSION: Our results confirm the necessity for an assessment of perfusion both before and shortly after angioplasty, since it provides the best documentation of the changes in myocardial perfusion.
Armaghan Fard-Esfahani; Majid Assadi; Mohsen Saghari; Abbas Mohagheghie; Babak Fallahi; Mohammad Eftekhari; Davood Beiki; Abbas Takavar; Iraj Nabipour; Abdolali Ebrahimi; Sina Izadyar; Kianoush Ansari-Gilani
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē     Volume:  50     ISSN:  2241-5955     ISO Abbreviation:  Hellenic J Cardiol     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-09-21     Completed Date:  2009-12-14     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  101257381     Medline TA:  Hellenic J Cardiol     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  396-401     Citation Subset:  IM    
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MeSH Terms
Angioplasty, Balloon, Coronary*
Coronary Angiography
Coronary Artery Disease / radiography*,  therapy*
Coronary Circulation
Middle Aged
Myocardial Perfusion Imaging*
Tomography, Emission-Computed, Single-Photon

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