| The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis. | |
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MedLine Citation:
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PMID: 20549139 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Micro-ribonucleic acids (microRNAs) are small molecules containing 20-23 nucleotides. Despite their small size, it is likely that almost every cellular process is regulated by them. Moreover, aberrant microRNA expression has been involved in the development of various diseases, including cancer. Although many data are available about the role of microRNAs in various lymphoproliferative disorders, their impact on the development of acute lymphoblastic leukemia of T-cell progenitors is largely unknown. In this review, we present recent information about how specific microRNAs are expressed and regulated during malignant T-lymphopoiesis and about their role during normal hematopoiesis. |
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Authors:
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S N Slavov; H L Gimenes Teixeira; E M Rego |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-06-11 |
Journal Detail:
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Title: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] Volume: 43 ISSN: 1414-431X ISO Abbreviation: Braz. J. Med. Biol. Res. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8112917 Medline TA: Braz J Med Biol Res Country: Brazil |
Other Details:
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Languages: eng Pagination: 619-26 Citation Subset: IM |
Affiliation:
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Divisão de Hematologia/Oncologia, Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto e Instituto Nacional de Ciência e Tecnologia em Células-Tronco e Terapia Celular, Universidade de São Paulo, Ribeirão Preto, SP, Brasil. |
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