Document Detail


The role of metabolic acidosis in causing uremic hyperphosphatemia.
MedLine Citation:
PMID:  3007964     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Metabolic acidosis was corrected within 1 h in 7 chronic anuric uremic patients on maintenance hemodialysis and, in the course of a week, in 11 other patients on conservative therapy. These patients were on a diet supplying constant amounts of phosphate throughout the duration of the study. In the former group the intravenous infusion of sodium bicarbonate was used, and, in the latter, the oral administration of sodium citrate. In both groups serum phosphate was found to decrease significantly. In the patients on conservative therapy, phosphaturia also had significantly decreased while no changes occurred in their daily fecal loss of phosphate that was measured in 3 patients. These findings indicate that metabolic acidosis is one of the causes of hyperphosphatemia in chronic uremic patients.
Authors:
G Barsotti; M Lazzeri; C Cristofano; M Cerri; S Lupetti; S Giovannetti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mineral and electrolyte metabolism     Volume:  12     ISSN:  0378-0392     ISO Abbreviation:  Miner Electrolyte Metab     Publication Date:  1986  
Date Detail:
Created Date:  1986-04-29     Completed Date:  1986-04-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802196     Medline TA:  Miner Electrolyte Metab     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  103-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acidosis / blood*,  complications,  drug therapy
Bicarbonates / therapeutic use
Citrates / therapeutic use
Citric Acid
Feces / analysis
Female
Humans
Male
Phosphates / blood*
Sodium / therapeutic use
Sodium Bicarbonate
Uremia / blood*,  complications
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Citrates; 0/Phosphates; 144-55-8/Sodium Bicarbonate; 7440-23-5/Sodium; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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