| The role of mesalazine in Crohn's disease. | |
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MedLine Citation:
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PMID: 1972296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sulfasalazine continues to be a common treatment for active Crohn's disease. It has been shown to be more effective than placebo in patients with colonic disease and in patients without prior surgical resection. There is no clear clinical evidence for its use as maintenance therapy in quiescent Crohn's disease; nevertheless, it is widely used to prevent symptom recurrence in patients whose active disease responded to sulfasalazine. In a few preliminary controlled studies, mesalazine has been shown to be superior to placebo in the treatment of active Crohn's disease. Until recently, the results of trials of mesalazine as maintenance therapy in quiescent Crohn's disease were equivocal but promising. |
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Authors:
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S B Hanauer |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Scandinavian journal of gastroenterology. Supplement Volume: 172 ISSN: 0085-5928 ISO Abbreviation: Scand. J. Gastroenterol. Suppl. Publication Date: 1990 |
Date Detail:
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Created Date: 1990-07-13 Completed Date: 1990-07-13 Revised Date: 2008-02-13 |
Medline Journal Info:
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Nlm Unique ID: 0437034 Medline TA: Scand J Gastroenterol Suppl Country: NORWAY |
Other Details:
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Languages: eng Pagination: 56-9 Citation Subset: IM |
Affiliation:
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Dept. of Medicine, University of Chicago Medical Center, Illinois 60637. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aminosalicylic Acids
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therapeutic use* Crohn Disease / drug therapy* Humans Mesalamine Sulfasalazine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Aminosalicylic Acids; 599-79-1/Sulfasalazine; 89-57-6/Mesalamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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