| The role of lymphoscintigraphy in the diagnosis of lymphedema in Turner syndrome. | |
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MedLine Citation:
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PMID: 19927901 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lymphedema can be present in patients affected by Turner syndrome (TS) with the dorsum of the hands and feet most commonly affected. This lymphedema results from underdevelopment of the lymphatic system before birth, and it usually decreases during childhood. The aim of our study was to evaluate the role of lymphoscintigraphy as a diagnostic tool in patients with TS to assess possible impairments in the lymphatic system. Eighteen patients with TS were karyotyped to confirm diagnosis and were evaluated by lymphoscintigraphy. Lymphatic dysfunction was demonstrated in 15/18 patients. Lymphoscintigraphic studies showed: 1) lymphatic channels, 2) collateral lymphatic channels, 3) interrupted lymphatic structures, and 4) lymph nodes of the deep lymphatic system. Our data demonstrate that lymphoscintigraphy should be mandatory not only in patients affected by Turner syndrome with signs of lymphatic dysplasia but also in those with minimal or absent signs of lymphatic impairment in order to obtain a very early diagnosis and to provide substantial information for possible medical or surgical treatment. |
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Authors:
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C Bellini; E Di Battista; F Boccardo; C Campisi; G Villa; G Taddei; C Traggiai; A Amisano; A Amisamo; P Polo Perucchin; C S Benfenati; E Bonioli; R Lorini |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Lymphology Volume: 42 ISSN: 0024-7766 ISO Abbreviation: Lymphology Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-11-20 Completed Date: 2009-12-23 Revised Date: 2010-03-11 |
Medline Journal Info:
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Nlm Unique ID: 0155112 Medline TA: Lymphology Country: United States |
Other Details:
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Languages: eng Pagination: 123-9 Citation Subset: IM |
Affiliation:
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Neuromuscular Diseases Unit, Department of Pediatrics, University of Genoa, Genoa, Italy. carlobellini@ospedale-gaslini.ge.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Female Humans Lymphedema / radionuclide imaging* Male Radiopharmaceuticals / diagnostic use Technetium Tc 99m Aggregated Albumin / diagnostic use Turner Syndrome / radionuclide imaging* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 0/Technetium Tc 99m Aggregated Albumin; 0/technetium Tc 99m nanocolloid |
| Comments/Corrections | |
Erratum In:
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Lymphology. 2009 Dec;42(4):202 Note: Amisamo, A [corrected to Amisano, A] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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