| The role of lipid profile as a risk factor indicator for ischemic stroke at Cipto Mangunkusumo Hospital, Jakarta. | |
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MedLine Citation:
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PMID: 16479026 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: to determine the role of low HDL-cholesterol, and high total cholesterol, LDL-Cholesterol and triglyceride as risk factors for ischemic stroke at Dr. Cipto Mangunkusumo Hospital. METHOD: a study was conducted on 76 patients with an age range of 40-70 years. Subjects consisted of 38 post ischemic stroke patients and 38 control subjects with a diagnosis other than stroke. The study sample consisted of serum for lipid profile assessment. Total cholesterol and triglyceride were assessed using enzymatic method, while HDL-cholesterol and LDL-cholesterol using direct homogenous enzymatic method. Statistical analysis was performed using chi-square and multivariate analysis using logistic regression. RESULTS: low HDL-cholesterol was found in ischemic stroke patients and demonstrated a significant difference compared to control subjects (p<0.05). The results of total cholesterol, triglyceride, LDL-cholesterol did not demonstrate a significant difference. The odds ratio (3.09; CI 95%: 1.04; 8.73) demonstrates that low HDL-cholesterol is a risk factor for ischemic stroke. CONCLUSION: a low HDL-cholesterol level is a risk factor for ischemic stroke, with an odds ratio of 3.09, while total cholesterol, triglyceride and high LDL-cholesterol levels were not risk factors for ischemic stroke. |
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Authors:
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Suzanna Immanuel; Astuti Giantini; Rahajuningsih S Dharma; |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta medica Indonesiana Volume: 38 ISSN: 0125-9326 ISO Abbreviation: Acta Med Indones Publication Date: 2006 Jan-Mar |
Date Detail:
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Created Date: 2006-02-15 Completed Date: 2006-09-05 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7901042 Medline TA: Acta Med Indones Country: Indonesia |
Other Details:
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Languages: eng Pagination: 11-6 Citation Subset: IM |
Affiliation:
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Departement of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Brain Ischemia / blood*, epidemiology* Chi-Square Distribution Cholesterol, HDL / blood Cholesterol, LDL / blood Female Humans Indonesia / epidemiology Middle Aged Multivariate Analysis Risk Factors Stroke / blood*, epidemiology* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides |
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