Document Detail


On the role of lipid-bilayer elasticity for the lipid-protein interaction and the indirect protein-protein coupling.
MedLine Citation:
PMID:  6093965     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present paper deals with the curvature (or splay) elasticity of lipid bilayers and its possible consequences for the microscopic organization of membranes. Experimental studies of the microstructure of lipid-lipid and lipid-protein mixtures are reported and discussed in terms of this type of membrane elasticity. In particular, evidence is provided that the elastic distortion of lipid bilayers caused by the incorporation of proteins can lead to mechanisms of the indirect protein-protein interaction. Finally the question is discussed whether these mechanisms could also play a role for the formation of enzyme complexes in biological membranes.
Authors:
E Sackmann; R Kotulla; F J Heiszler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire     Volume:  62     ISSN:  0714-7511     ISO Abbreviation:  Can. J. Biochem. Cell Biol.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1985-01-14     Completed Date:  1985-01-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8302763     Medline TA:  Can J Biochem Cell Biol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  778-88     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Dimyristoylphosphatidylcholine*
Elasticity
Glycophorin
Lipid Bilayers*
Membrane Lipids / physiology*
Membrane Proteins / physiology*
Models, Biological
Molecular Conformation
Polymyxins
Chemical
Reg. No./Substance:
0/Glycophorin; 0/Lipid Bilayers; 0/Membrane Lipids; 0/Membrane Proteins; 0/Polymyxins; 13699-48-4/Dimyristoylphosphatidylcholine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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