| The role and limitations of mammary ductoscope in management of pathologic nipple discharge. | |
| | |
MedLine Citation:
|
PMID: 18673337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Mammary ductoscope allows visualization of the breast ductal wall and sampling of the abnormal area for diagnostic purposes. We are reporting our center experience in application of mammary ductoscope in detecting the underlying etiology of pathologic nipple discharge. Between November 2005 and December 2006 a total of 54 women, with spontaneous persistent nonlactational unilateral uniductal nipple discharge of no palpable lesions and negative breast sono-mammography, were included in the study for morphologic assessment of ductal epithelium, ductal lavage and ductoscopically guided procedures as punch biopsy and ductoscopically guided microdochectomy. Forty-one patients (76%) with nipple discharge were positive ductoscopically. Thirteen patients (24%) appeared normal. Ductoscopic lavage has a much more cellular yield than ordinary squeezing cytology. Ductal thickening by the ductoscope (11 cases) revealed to be hyperplasia on pathology (five cases), papilloma (two cases), atypical ductal hyperplasia (two cases), ductal carcinoma in situ (one case), and invasive breast carcinoma (one case). There was a significant association between intraductal visual observations and histopathologic diagnosis. Mammary Ductoscope is a promising tool in management of pathologic nipple discharge. Biopsy and ablation techniques can be performed during ductoscopy with correlation between visual findings and histopathology, but there are still some limitations of in clinical practice. |
| | |
Authors:
|
Adel Denewer; Khalil El-Etribi; Nadia Nada; Mohamed El-Metwally |
Related Documents
:
|
16374817 - Clinical and pathological characterization of progressive aphasia. 20345357 - Utility of pathologic evaluation following removal of explanted orthopaedic internal fi... 15252317 - Error in surgical pathology. 7193317 - Massive ovarian edema: review of world literature and report of two cases. 19681297 - Hemoperitoneum caused by the rupture of a giant ovarian teratoma in a 9-year-old female... 14499047 - Post-kala-azar dermal leishmaniasis associated with aids. |
Publication Detail:
|
Type: Journal Article Date: 2008-07-30 |
Journal Detail:
|
Title: The breast journal Volume: 14 ISSN: 1524-4741 ISO Abbreviation: Breast J Publication Date: 2008 Sep-Oct |
Date Detail:
|
Created Date: 2008-09-29 Completed Date: 2008-11-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9505539 Medline TA: Breast J Country: United States |
Other Details:
|
Languages: eng Pagination: 442-9 Citation Subset: IM |
Affiliation:
|
Department of Surgical Oncology, Oncology Center, Mansoura University, Mansoura, Eqypt. adeldenewer@mans.edu.eg |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Biopsy, Fine-Needle Breast Diseases / diagnosis Breast Neoplasms / diagnosis, pathology*, ultrasonography Carcinoma, Ductal, Breast / pathology, ultrasonography Carcinoma, Intraductal, Noninfiltrating / pathology, ultrasonography Carcinoma, Lobular / pathology, ultrasonography Cohort Studies Diagnosis, Differential Endoscopy / methods* Exudates and Transudates / cytology* Female Fiber Optic Technology / methods Humans Middle Aged Nipples / pathology*, secretion* Probability Risk Assessment Sensitivity and Specificity Ultrasonography, Mammary |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of a low dose of equine purified FSH to induce multiple ovulations in mares.
Next Document: Presence of a micropapillary pattern in mucinous carcinomas of the breast and its impact on the clin...