Document Detail

The role of leiomyomas in infertility.
MedLine Citation:
PMID:  10548702     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To assess the role of leiomyomas and their surgical removal on pregnancy rates.
DESIGN: (Canadian Task Force classification II-1). Setting. Academic center.
PATIENTS: Two hundred twelve women who were investigated for infertility.
INTERVENTION: Laparoscopic myomectomy.
MEASUREMENTS AND MAIN RESULTS: Patients were divided according to case control criteria as those who underwent laparoscopic removal of myomas (106) and those who did not (106); both groups were compared with 106 women with unexplained infertility without myomas. Of the 318 women, 83 (26%) became pregnant and delivered live infants. The 44 (42%) who underwent surgical removal of leiomyomas had higher delivery rates than 12 (11%) who did not undergo surgery (p <0.001) and 27 (25%) who did not have myomas (p <0.001). Patients whose myomas were not surgically treated had fewer deliveries than women who did not have myomas (12 vs 27, p <0.002). Fifteen women had spontaneous abortions before week 12: 3 (3%) who had surgery, 10 (9%) who did not have surgery, and 2 (2%) who did not have myomas.
CONCLUSION: Laparoscopic myomectomy improved pregnancy rates over nonsurgical management of myomas.
C Bulletti; D De Ziegler; V Polli; C Flamigni
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the American Association of Gynecologic Laparoscopists     Volume:  6     ISSN:  1074-3804     ISO Abbreviation:  J Am Assoc Gynecol Laparosc     Publication Date:  1999 Nov 
Date Detail:
Created Date:  1999-12-22     Completed Date:  1999-12-22     Revised Date:  2013-08-01    
Medline Journal Info:
Nlm Unique ID:  9417443     Medline TA:  J Am Assoc Gynecol Laparosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  441-5     Citation Subset:  IM    
Center for Special Pelvic Surgery, University of Bologna, Bologna, Italy.
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MeSH Terms
Infertility, Female / etiology*
Leiomyoma / complications*,  pathology,  surgery
Uterine Neoplasms / complications*,  pathology,  surgery

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