Document Detail


The role of lateral occipital face and object areas in the face inversion effect.
MedLine Citation:
PMID:  21896279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stimulus inversion impairs face discrimination to a greater extent than discrimination of other non-face object categories. This finding has led to suggestions that upright faces are represented by mechanisms specialized for upright faces whereas inverted face representation depends on more general object recognition mechanisms. In the present study we tested the causal role of face-selective and object-selective cortical areas for upright and inverted face discrimination by transiently disrupting neural processing using transcranial magnetic stimulation (TMS). Participants matched upright and inverted faces while TMS was delivered over each participant's functionally localized right occipital face area (rOFA) or right lateral occipital area (rLO). TMS delivered over rOFA disrupted the discrimination of upright and inverted faces while TMS delivered over rLO impaired inverted face discrimination only. These results provide causal evidence that upright faces are represented by face-specific mechanisms whereas inverted faces are represented by both face-specific and object-specific mechanisms. The similar sensitivity of the OFA to upright and inverted faces is consistent with the hypothesis that the OFA processes facial features at an early stage of face processing.
Authors:
David Pitcher; Bradley Duchaine; Vincent Walsh; Galit Yovel; Nancy Kanwisher
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-08-30
Journal Detail:
Title:  Neuropsychologia     Volume:  49     ISSN:  1873-3514     ISO Abbreviation:  Neuropsychologia     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-12     Completed Date:  2012-02-14     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  0020713     Medline TA:  Neuropsychologia     Country:  England    
Other Details:
Languages:  eng     Pagination:  3448-53     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Brain Mapping*
Face*
Female
Functional Laterality / physiology*
Humans
Magnetic Resonance Imaging
Male
Occipital Lobe / physiology*
Pattern Recognition, Visual / physiology*
Photic Stimulation / methods
Reaction Time / physiology
Transcranial Magnetic Stimulation
Young Adult
Grant Support
ID/Acronym/Agency:
BB/F022875/1//Biotechnology and Biological Sciences Research Council; EY13455/EY/NEI NIH HHS; G0700929//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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