| The role of laminin in embryonic cell polarization and tissue organization. | |
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MedLine Citation:
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PMID: 12737798 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Genetic analyses have revealed that members of the laminin glycoprotein family are required for basement membrane assembly and cell polarization, with subsequent effects on cell survival and tissue organization during metazoan embryogenesis. These functions depend upon the cooperation between laminin polymerization and cell anchorage mediated via interactions with beta1-integrins, dystroglycan, and other cell surface receptors. |
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Authors:
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Shaohua Li; David Edgar; Reinhard Fässler; William Wadsworth; Peter D Yurchenco |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Developmental cell Volume: 4 ISSN: 1534-5807 ISO Abbreviation: Dev. Cell Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-09 Completed Date: 2003-06-16 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 101120028 Medline TA: Dev Cell Country: United States |
Other Details:
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Languages: eng Pagination: 613-24 Citation Subset: IM |
Affiliation:
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Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Apoptosis Basement Membrane / cytology, embryology Cell Adhesion Cell Polarity* Epithelial Cells / cytology Laminin / metabolism* Stem Cells / cytology, ultrastructure |
| Grant Support | |
ID/Acronym/Agency:
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DK36425/DK/NIDDK NIH HHS; NS38469/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Laminin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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