| The role of inflammation in atrial fibrillation following open heart surgery. | |
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MedLine Citation:
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PMID: 18831903 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study investigated the role of systemic inflammation in the development of atrial fibrillation (AF) after coronary artery bypass grafting (CABG). CABG was performed using cardiopulmonary bypass in 77 patients. Pre-operative AF was present in six patients (7.8%) and postoperative AF developed in 13 (18.3%) of the 71 patients with pre-operative sinus rhythm. Post-operative mediastinal drainage was significantly increased in patients with post-operative AF compared with those with sinus rhythm. Plasma E-selectin, P-selectin and vascular cell adhesion molecule levels were not significantly different between patients with pre- and post-operative sinus rhythm, those with pre-operative sinus rhythm and post-operative AF, and those with pre- and post-operative AF. There were significant differences between pre- and post-operative C-reactive protein, interleukin (IL)-6 and IL-10 levels within all three groups, but no differences in these parameters between the groups. Thus, in all groups there were significant alterations in mediators indicative of systemic inflammation following CABG, but comparisons between the groups revealed no differences predictive of AF. |
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Authors:
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S Canbaz; H Erbas; S Huseyin; E Duran |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of international medical research Volume: 36 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-10-03 Completed Date: 2008-10-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 1070-6 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Surgery, Medical Faculty, Trakya University, Edirne, Turkey. scanbaz@trakya.edu.tr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atrial Fibrillation* / etiology, immunology Biological Markers / metabolism C-Reactive Protein / metabolism Cardiopulmonary Bypass Coronary Artery Bypass / adverse effects* Female Humans Inflammation / metabolism* Interleukin-10 / blood Interleukin-6 / blood Male Middle Aged Postoperative Complications |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Interleukin-6; 130068-27-8/Interleukin-10; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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