Document Detail


The role of the immune system in severe ovarian hyperstimulation syndrome.
MedLine Citation:
PMID:  8569544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ovarian hyperstimulation syndrome is a serious, and potentially life-threatening, complication of ovulation induction. Hitherto, there has been no reliable test which will predict patients who will subsequently develop ovarian hyperstimulation syndrome. Recently, evidences have accumulated concerning the interaction between the immune and reproductive systems which results from sharing certain lymphohaematopoietic cytokines and their receptors. Furthermore, several cytokines have been implicated in the prediction and pathophysiology of ovarian hyperstimulation syndrome. If this is true, it may be possible to modify the patients' immunological homeostasis by passive immunization with intravenous immunoglobulin (IVIg) and thus to prevent ovarian hyperstimulation syndrome.
Authors:
R Orvieto; Z Ben-Rafael
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical hypotheses     Volume:  45     ISSN:  0306-9877     ISO Abbreviation:  Med. Hypotheses     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1996-03-05     Completed Date:  1996-03-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505668     Medline TA:  Med Hypotheses     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  231-4     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Golda Medical Center (Hasharon Hospital), Petah Tiqva, Israel.
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MeSH Terms
Descriptor/Qualifier:
Albumins / therapeutic use
Animals
Body Fluids / chemistry
Corpus Luteum Maintenance / drug effects
Disease Susceptibility / diagnosis
Estradiol / blood
Female
Homeostasis
Humans
Immunization, Passive
Immunoglobulins, Intravenous / therapeutic use
Interleukin-2 / physiology*
Models, Immunological
Ovarian Follicle / metabolism*
Ovarian Hyperstimulation Syndrome / immunology*,  prevention & control
Pregnancy
Rabbits
Chemical
Reg. No./Substance:
0/Albumins; 0/Immunoglobulins, Intravenous; 0/Interleukin-2; 50-28-2/Estradiol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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