| The role of high frequency oscillatory ventilation in very preterm infants. | |
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MedLine Citation:
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PMID: 12011563 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The role of high frequency oscillatory ventilation (HFOV) for the treatment of respiratory disease in preterm infants remains uncertain. Animal work demonstrates reduced lung injury with HFOV compared to conventional ventilation (CV), and previous human trials suggest that in preterm infants HFOV reduces the incidence of chronic lung disease (CLD). However, the trials themselves have several limitations. In an attempt to conclusively establish the role of HFOV for the prevention of CLD in very preterm infants we conducted a large, UK based, multicentre trial. Preliminary results of this study suggest there are no significant differences between the two modes of ventilation regarding mortality and incidence of CLD. |
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Authors:
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Sandra Calvert |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Biology of the neonate Volume: 81 Suppl 1 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 2002 |
Date Detail:
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Created Date: 2002-05-15 Completed Date: 2002-09-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: Switzerland |
Other Details:
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Languages: eng Pagination: 25-7 Citation Subset: IM |
Copyright Information:
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Copyright 2002 S. Karger AG, Basel |
Affiliation:
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Department Child Health, St. George's Hospital, London, UK. salvert@sghms.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chronic Disease Clinical Trials as Topic High-Frequency Ventilation* / adverse effects Humans Infant, Newborn Infant, Premature* Lung Diseases / prevention & control* Multicenter Studies as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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