| The role of free radicals in airway obstruction in asthmatic patients. | |
| | |
MedLine Citation:
|
PMID: 1657539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Neutrophils from asthmatic patients seem to be in an activated state. This study demonstrated that superoxide radical (O2-) production was enhanced in asthmatic patients compared with healthy control subjects. Production of (O2-) also increased with progression of disease and with disease duration. In addition, (O2-) release was inversely correlated with FEV1 and midflows and was greater in neutrophils from patients with exacerbated disease than in those from patients with stable disease. These findings suggest that oxygen metabolites may play a direct or indirect role in the modulation of airway inflammation. |
| | |
Authors:
|
H Kanazawa; N Kurihara; K Hirata; T Takeda |
Related Documents
:
|
23185799 - Correlation of human papilloma virus infection with cytology, colposcopy and histopatho... 23075639 - Diffuse alopecia areata is associated with intense inflammatory infiltration and cd8+ t... 1066319 - Leukocyte migration inhibition by cancer patients' sera. 23682929 - Bilateral pallidal stimulation for "sticking-out tongue" feature in patients with prima... 23370589 - Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone ... 23001109 - Bickerstaff's brainstem encephalitis associated with ulcerative colitis. 12975539 - Elevated serum ca 125 levels in mitral stenotic patients with heart failure. 15354979 - Improved anemia and reduced erythropoietin need by medical or surgical intervention of ... 7303049 - Marantic endocarditis in children and young adults: clinical and pathological findings. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Chest Volume: 100 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1991 Nov |
Date Detail:
|
Created Date: 1991-12-03 Completed Date: 1991-12-03 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1319-22 Citation Subset: AIM; IM |
Affiliation:
|
First Department of Internal Medicine, Osaka City University Medical School, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Airway Obstruction / etiology, physiopathology Asthma / physiopathology* Female Humans Lymphocyte Activation / physiology Male Middle Aged Neutrophils / physiology* Respiratory Function Tests Superoxides / blood* |
| Chemical | |
Reg. No./Substance:
|
11062-77-4/Superoxides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bilateral bronchoalveolar lavage in the diagnosis of opportunistic pulmonary infections.
Next Document: Limitations of the fast green assay for chemosensitivity testing in human lung cancer.