| The role of essential fatty acids in development. | |
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MedLine Citation:
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PMID: 16011478 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The presence of docosahexaenoic acid (DHA) and arachidonic acid (ARA) in human milk but not in infant formula, coupled with lower plasma and brain lipid contents of DHA in formula-fed than in breast-fed infants and reports of higher IQ in individuals who were breast-fed versus formula-fed as infants, suggest that exogenous DHA (and ARA) may be essential for optimal development. Thus, since 1990, several studies have examined the impact of formulas containing DHA or DHA plus ARA on visual function and neurodevelopmental outcome. Some of these studies have shown benefits but others have not. These results leave largely unanswered the question of whether these fatty acids are beneficial for either the term or preterm infant. However, evidence that preterm infants might benefit is somewhat more convincing than that for term infants. Despite the limited evidence for efficacy, formulas supplemented with DHA and ARA are now available and appear to be safe. |
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Authors:
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William C Heird; Alexandre Lapillonne |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annual review of nutrition Volume: 25 ISSN: 0199-9885 ISO Abbreviation: Annu. Rev. Nutr. Publication Date: 2005 |
Date Detail:
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Created Date: 2005-07-13 Completed Date: 2005-09-29 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8209988 Medline TA: Annu Rev Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 549-71 Citation Subset: IM |
Affiliation:
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Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030-2600, USA. wheird@bcm.tmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arachidonic Acid
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physiology Behavior Brain / physiology Child, Preschool Cognition Docosahexaenoic Acids Fatty Acids, Essential / physiology* Fatty Acids, Unsaturated / pharmacology, physiology Female Growth / physiology* Humans Infant Infant Nutritional Physiological Phenomena Infant, Newborn Milk, Human / chemistry Vision, Ocular |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Essential; 0/Fatty Acids, Unsaturated; 25167-62-8/Docosahexaenoic Acids; 506-32-1/Arachidonic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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