Document Detail

The role of echocardiography in suspected and established PE.
MedLine Citation:
PMID:  15199499     Owner:  NLM     Status:  MEDLINE    
Acute obstruction of more than 30% of the pulmonary arterial bed often results in abnormal right ventricular (RV) transthoracic Doppler echocardiography (TTE), usually defined as RV dysfunction, dilatation, or hypokinesis. The presence of such changes strongly increases the clinical probability of pulmonary embolism (PE) (specificity, 81 to 94%; PPV, 71 to 86%) and indicates a worse prognosis, especially if a patent foramen ovale is found at contrast TTE. Normal RV echocardiography indicates a good prognosis. Integrating TTE with venous ultrasound and transesophageal imaging increases the possibility of immediate definitive justification for specific therapy. This strategy permits direct visualization of thrombi either in proximal veins, pulmonary arteries, or right heart chambers. Mobile thrombi require immediate thrombolysis or urgent embolectomy. Whether any echo-based criteria might identify normotensive patients with PE who should receive thrombolytic therapy remains a subject for an overdue large prospective trial.
A Torbicki; P Pruszczyk
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in vascular medicine     Volume:  1     ISSN:  1528-9648     ISO Abbreviation:  Semin Vasc Med     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2004-06-16     Completed Date:  2004-07-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100940307     Medline TA:  Semin Vasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  165-74     Citation Subset:  IM    
Department of Chest Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.
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MeSH Terms
Echocardiography, Doppler*
Heart Septal Defects, Atrial / complications
Hypertension, Pulmonary / complications
Predictive Value of Tests
Pulmonary Embolism / complications,  physiopathology,  ultrasonography*
Risk Factors
Sensitivity and Specificity
Ventricular Dysfunction, Right / etiology,  ultrasonography
Ventricular Function, Right

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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