Document Detail

The role of cortical evoked responses in predicting neuromotor outcome in very preterm infants.
MedLine Citation:
PMID:  10735459     Owner:  NLM     Status:  MEDLINE    
To explore the role of posterior tibial somatosensory evoked potentials (SSEP) and flash visual evoked potentials (VEP) in the early prediction of functional brain injury, 93 infants of less than 32 weeks gestation at birth were studied. Neuromotor outcome was defined by clinical examination at the age of 2 years. SSEP, VEP and cerebral ultrasound were compared as predictors of neuromotor outcome. Posterior tibial SSEP were the most accurate single method of predicting neuromotor abnormalities with a 83% positive predictive power for cerebral palsy and a 100% predictive power for abnormal neurology, compared to 17% and 40% for cerebral ultrasound and 38% and 85% for VEP respectively. When SSEP and VEP results were concordant, the positive predictive power for cerebral palsy and abnormal neurology was 100%. Our results suggest that posterior tibial SSEP and VEP are accurate tools in the prediction of outcome in very preterm infants.
A A Pike; N Marlow
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Early human development     Volume:  57     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-04-14     Completed Date:  2000-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  123-35     Citation Subset:  IM    
Department of Child Health, St. Michael 's Hospital, Bristol, UK.
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MeSH Terms
Cerebral Palsy / diagnosis*,  physiopathology
Dystonia / diagnosis,  physiopathology
Evoked Potentials, Somatosensory*
Evoked Potentials, Visual*
Gestational Age
Infant, Newborn
Infant, Premature / physiology*

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