| The role of continuous positive airway pressure during weaning from mechanical ventilation in cardiac surgical patients. | |
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MedLine Citation:
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PMID: 7645695 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the effects of providing patients with continuous positive airway pressure during a short weaning period from mechanical ventilation to extubation. Following elective primary aortocoronary bypass surgery employing cardiopulmonary bypass, 80 patients received intermittent positive pressure ventilation for 5 h. At the end of this time patients were randomly allocated to one of the following three groups for a 2 h period of spontaneous respiration prior to extubation: group CPAP0 = T-piece circuit (n = 27); group CPAP5 = 5 cmH2O of continuous positive airway pressure (n = 27); group CPAP10 = 10 cmH2O of continuous positive airway pressure (n = 26). Following extubation, pulmonary gas exchange was assessed after 1, 2, 4, and 24 h. All patients had good pre-operative lung function. There was a significant increase in the median alveolar-arterial oxygen partial pressure difference and a decrease in the oxygenation index in all three groups during the period of added inspired oxygen which persisted until 24 h post-extubation, but there were no differences between the groups. In patients with good pre-operative lung function requiring primary aortocoronary bypass surgery, the use of continuous positive airway pressure confers no advantage over a simple T-piece attachment during the short period of weaning from mechanical ventilation to extubation. |
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Authors:
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C R Bailey; R M Jones; A A Kelleher |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Anaesthesia Volume: 50 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-09-15 Completed Date: 1995-09-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 677-81 Citation Subset: AIM; IM |
Affiliation:
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S.E. Thames Cardiothoracic Unit, Brook General Hospital, London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Artery Bypass Female Humans Male Middle Aged Partial Pressure Positive-Pressure Respiration* Pulmonary Gas Exchange Ventilator Weaning* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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