Document Detail


The role of conservative management in congenital tracheal stenosis: an evidence-based long-term follow-up study.
MedLine Citation:
PMID:  16818049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/PURPOSE: Surgery has been the management of choice for severe congenital tracheal stenosis (CTS). The role of conservative management of CTS however is not clear. The aim of this study is to characterize the natural history of CTS, review the radiologic evidence of tracheal growth, and evaluate the clinical outcome and selection criteria of conservative management of CTS. METHODS: A retrospective study was carried out on 22 consecutive children with symptomatic CTS admitted into a single institution between 1982 and 2001. The patients were categorized into operation (n = 11) and observation (n = 11) groups. Six patients of the observation group were followed up with serial computed tomography scan. Their tracheal growth was compared with that of healthy children of the same age. RESULTS: The mortality rates of observation and operation groups were 9% and 27%, respectively, although the latter group consisted of more severely affected patients. The pathologic categorization of the CTS influenced the survival rates (P = .046, chi2), with the long segment type having the worst prognosis (67%). Serial computed tomography scans of 6 conservatively managed patients revealed that all stenotic tracheas continued to grow (P = .039, 2-tailed paired Student's t test). Of the 6 stenotic tracheas, 5 grew at a faster-than-normal rate, and the stenotic tracheal diameters approached those of normal diameters by the age of 9 years. CONCLUSIONS: The management of patients with symptomatic CTS should be individualized. A selected group of patients with CTS can be safely managed nonoperatively.
Authors:
Wei Cheng; David E Manson; Victor Forte; Sigmund H Ein; Ian MacLusky; Blake C Papsin; Sloan Hechter; Peter C W Kim
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  41     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-04     Completed Date:  2006-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1203-7     Citation Subset:  IM    
Affiliation:
Division of General Surgery, Department of Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada 5G 1X8.
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MeSH Terms
Descriptor/Qualifier:
Disease Progression
Female
Follow-Up Studies
Humans
Infant
Male
Patient Selection
Retrospective Studies
Trachea / growth & development
Tracheal Stenosis / congenital,  mortality,  therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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