| The role of central and peripheral cholecystokinin in mediating appetitive behaviors. | |
| | |
MedLine Citation:
|
PMID: 6289285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cholecystokinin (CCK) reduces total food consumption in mice, rats, pigs, sheep, monkeys and humans. Behaviors associated with an underlying state of satiety are reported after CCK administration. Reductions in exploration and social interactions by CCK are not due to true sedation or sleep, as measured by cortical EEG recordings. The satiety effects appear to be mediated by peripheral CCK receptors, through a feedback loop involving the vagus nerve. The conceptual link between the behavioral functions of CCK as a putative satiety signal and its established digestive functions are discussed. |
| | |
Authors:
|
J N Crawley; J A Rojas-Ramirez; W B Mendelson |
Related Documents
:
|
10713285 - Intraaccumbens baclofen selectively enhances feeding behavior in the rat. 8971925 - Effects of cholecystokinin octapeptide (cck-8) on food intake in adult and aged rats un... 1672115 - Influence of food deprivation on intestinal cholecystokinin and somatostatin. 7195655 - Stress-induced eating in rats. 1478315 - The relationship between central nuclear scatter and perinuclear retrodots in the human... 20153065 - Cryptosporidium oocysts on fresh produce from areas of high livestock production in pol... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Peptides Volume: 3 ISSN: 0196-9781 ISO Abbreviation: Peptides Publication Date: 1982 May-Jun |
Date Detail:
|
Created Date: 1982-12-02 Completed Date: 1982-12-02 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8008690 Medline TA: Peptides Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 535-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Appetitive Behavior / drug effects* Cholecystokinin / pharmacology* Mice Rats Receptors, Cell Surface / drug effects Receptors, Cholecystokinin Satiety Response / drug effects Sleep / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Receptors, Cell Surface; 0/Receptors, Cholecystokinin; 9011-97-6/Cholecystokinin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of desmopressin acetate (DDAVP) on the learning of a brightness discrimination.
Next Document: Modulation of [3H]-dopamine binding by cholecystokinin octapeptide (CCK-8).