Document Detail


The role of the central nervous system in sudden cardiac death: heartbeat dynamics in conscious pigs during coronary occlusion, psychologic stress and intracerebral propranolol.
MedLine Citation:
PMID:  7696132     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electrocardiograms were recorded in conscious pigs during psychological stress (touching), left anterior descending coronary artery occlusion, intracerebral levopropranolol (0.05 mg/kg), and their respective controls. The R-R intervals were evaluated with both a deterministic measure (point correlation dimension) and a stochastic one (mean). Only the deterministic measure was sensitive to between-subject responses (P < .01), whereas both measures were sensitive to within-subject changes. The results are explained by a deterministic model of heartbeat generation.
Authors:
J E Skinner
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Integrative physiological and behavioral science : the official journal of the Pavlovian Society     Volume:  29     ISSN:  1053-881X     ISO Abbreviation:  Integr Physiol Behav Sci     Publication Date:    1994 Oct-Dec
Date Detail:
Created Date:  1995-05-03     Completed Date:  1995-05-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9105843     Medline TA:  Integr Physiol Behav Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-61     Citation Subset:  IM    
Affiliation:
Totts Gap Medical Research Laboratories, Bangor, PA 18013.
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MeSH Terms
Descriptor/Qualifier:
Animals
Central Nervous System / physiopathology*
Coronary Vessels / physiopathology*
Death, Sudden, Cardiac / etiology*
Electrocardiography / drug effects
Heart Rate / physiology*
Injections, Intraventricular
Propranolol / administration & dosage,  pharmacology*
Stress, Psychological / physiopathology*
Swine
Grant Support
ID/Acronym/Agency:
NS 27745/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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