Document Detail


The role of cartilage canals in the formation of secondary centres of ossification.
MedLine Citation:
PMID:  541238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present studies indicate that in the growth of cartilage canals the cartilage is removed by chondroclasts which stem from the primitive connective tissue cells of the perichondrium. Besides fusing to form multinucleated chondroclasts, these cells also provide the osteoblasts which establish the secondary centre of ossification. The growing tips of the blood vessels within the canals are also fashioned from these primitive connective tissue cells as they invade the microhaemorrhages at the ends of the canals. This is an identical procedure to that found in the vascular invasion of the primary growth plate. The cartilage canals are clearly useful sites in which to study the development of osteoclasts and chondroclasts from more primitive (osteoprogenitor) cells.
Authors:
J H Kugler; A Tomlinson; A Wagstaff; S M Ward
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of anatomy     Volume:  129     ISSN:  0021-8782     ISO Abbreviation:  J. Anat.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-06-25     Completed Date:  1980-06-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0137162     Medline TA:  J Anat     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  493-506     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Vessels / ultrastructure
Cartilage / blood supply,  ultrastructure*
Cytoplasm / ultrastructure
Epiphyses / ultrastructure
Femur
Humerus
Osteoclasts / ultrastructure
Osteogenesis*
Rabbits
Rats
Comments/Corrections

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