Document Detail

The role of blood coagulability and axial streaming of erythrocytes in determining F cells-value and TPR.
MedLine Citation:
PMID:  495119     Owner:  NLM     Status:  MEDLINE    
Experiments were performed in anaesthetized and splenectomized dogs to influence the intravascular distribution of erythrocytes and plasma within the vascular bed. Blood volume was determined by double-isotope labelling of red cells and plasma. A significant decrease of F cells-value was found after posthaemorrhagic haemodilution and after haemodilution induced by homologous plasma. The administration of epsilon-amino caproic acid and bovine thrombin was followed by a significant increase of F cells-value. An interdependence of coagulability and F cells-value is suggested. The increase of haematocrit was followed by an increase of TPR, which, however, was only half of the value that would have been anticipated on the basis of the increase of viscosity when measured in normal-bore viscometers. This points to the possibility that blood flowing in the resistance vessels undergoes a certain spontaneous separation of cells and plasma and its haematocrit will be lower than in the large vessels. Cell separation in different organs having different haematocrit values and blood volumes probably affects total body haematocrit and F cells-value.
B Tanos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta physiologica Academiae Scientiarum Hungaricae     Volume:  53     ISSN:  0001-6756     ISO Abbreviation:  Acta Physiol Acad Sci Hung     Publication Date:  1979  
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0371156     Medline TA:  Acta Physiol Acad Sci Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
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MeSH Terms
Blood Circulation
Blood Coagulation
Blood Volume
Erythrocytes / physiology
Hemorrhage / physiopathology
Vascular Resistance*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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