Document Detail


The role of beta-endorphins and catechol estrogens on the hypothalamic-pituitary axis in female athletes.
MedLine Citation:
PMID:  6092153     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Competitive swimmers were followed over a 2-year period when they trained at different levels of exercise which coincided with distinct changes in their menstrual history. Oligomenorrhea was identified in 5 of 13 of these athletes when they swam approximately 100,000 yards per week. Weight and percentage of body fat were not significantly different between the period of oligomenorrhea and regular menstrual function (P = 0.24). Mean and median levels of luteinizing hormone, follicle-stimulating hormone, prolactin, and 17beta-estradiol were decreased and catechol estrogens and beta-endorphins were increased in serum during the strenuous, when compared with the moderate, training period. The serum levels of the steroid and protein hormones were similar to those of normal cycling, nonexercising control subjects during moderate exercise (60,000 yards per week). The significant differences between beta-endorphins and catechol estrogens during periods of strenuous exercise suggest an explanation for oligomenorrhea in female athletes. These hormonal changes result in hypothalamic anovulation, which appears to be reversible, because the hormone levels and menstrual cycles return to normal when the exercise is reduced.
Authors:
J B Russell; D E Mitchell; P I Musey; D C Collins
Related Documents :
21231913 - Is the beneficial effect of prior exercise on postprandial lipaemia partly due to redis...
11581003 - Effect of hydration on exercise-induced growth hormone response.
6708293 - The effect of isosorbide dinitrate on exertional hypotension in old myocardial infarction.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Fertility and sterility     Volume:  42     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1984-12-18     Completed Date:  1984-12-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  690-5     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Body Composition
Body Weight
Endorphins / blood,  physiology*
Estradiol / blood
Estrogens, Catechol / blood,  physiology*
Female
Follicle Stimulating Hormone / blood
Humans
Hypothalamo-Hypophyseal System / physiology*
Luteinizing Hormone / blood
Menstruation Disturbances / etiology*
Oligomenorrhea / etiology*
Physical Exertion*
Prolactin / blood
Sports Medicine*
Swimming
beta-Endorphin
Grant Support
ID/Acronym/Agency:
NIH-1-R01-AG-02012/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Endorphins; 0/Estrogens, Catechol; 50-28-2/Estradiol; 60617-12-1/beta-Endorphin; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Elevated plasma levels of beta-endorphin in a group of women with polycystic ovarian disease.
Next Document:  Endocrine and immunologic studies in a patient with resistant ovary syndrome.