| The role of beta-endorphins and catechol estrogens on the hypothalamic-pituitary axis in female athletes. | |
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MedLine Citation:
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PMID: 6092153 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Competitive swimmers were followed over a 2-year period when they trained at different levels of exercise which coincided with distinct changes in their menstrual history. Oligomenorrhea was identified in 5 of 13 of these athletes when they swam approximately 100,000 yards per week. Weight and percentage of body fat were not significantly different between the period of oligomenorrhea and regular menstrual function (P = 0.24). Mean and median levels of luteinizing hormone, follicle-stimulating hormone, prolactin, and 17beta-estradiol were decreased and catechol estrogens and beta-endorphins were increased in serum during the strenuous, when compared with the moderate, training period. The serum levels of the steroid and protein hormones were similar to those of normal cycling, nonexercising control subjects during moderate exercise (60,000 yards per week). The significant differences between beta-endorphins and catechol estrogens during periods of strenuous exercise suggest an explanation for oligomenorrhea in female athletes. These hormonal changes result in hypothalamic anovulation, which appears to be reversible, because the hormone levels and menstrual cycles return to normal when the exercise is reduced. |
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Authors:
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J B Russell; D E Mitchell; P I Musey; D C Collins |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Fertility and sterility Volume: 42 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1984 Nov |
Date Detail:
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Created Date: 1984-12-18 Completed Date: 1984-12-18 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 690-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Body Composition Body Weight Endorphins / blood, physiology* Estradiol / blood Estrogens, Catechol / blood, physiology* Female Follicle Stimulating Hormone / blood Humans Hypothalamo-Hypophyseal System / physiology* Luteinizing Hormone / blood Menstruation Disturbances / etiology* Oligomenorrhea / etiology* Physical Exertion* Prolactin / blood Sports Medicine* Swimming beta-Endorphin |
| Grant Support | |
ID/Acronym/Agency:
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NIH-1-R01-AG-02012/AG/NIA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Endorphins; 0/Estrogens, Catechol; 50-28-2/Estradiol; 60617-12-1/beta-Endorphin; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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