| The role of asthma management beliefs and behaviors in childhood asthma immune and clinical outcomes. | |
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MedLine Citation:
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PMID: 18689855 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: This study examined associations of asthma management-related beliefs and behaviors with immune markers and clinical outcomes in a sample of 66 children with asthma (ages 9-18 years). METHODS: Children and parents were interviewed about asthma management beliefs and behaviors. Immune measures included stimulated production of cytokines implicated in asthmatic airway inflammation, eosinophil counts, and IgE levels. Clinical outcomes included pulmonary function, symptoms, beta-agonist use, and physician contacts. RESULTS: Children's reports of greater conceptual understanding of asthma, parents' reports of quicker responses to asthma symptoms, and children's and parents' reports of more balanced integration of asthma into daily life were all associated with reduced inflammatory profiles. Inflammatory profiles were found to be a statistically significant pathway linking asthma beliefs and behaviors to clinical outcomes. CONCLUSIONS: These findings suggest that interventions aimed at teaching families better asthma management approaches may have the potential to alter biological profiles in children with asthma. |
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Authors:
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Hope A Walker; Louise Chim; Edith Chen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-08-09 |
Journal Detail:
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Title: Journal of pediatric psychology Volume: 34 ISSN: 1465-735X ISO Abbreviation: J Pediatr Psychol Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-23 Completed Date: 2009-07-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7801773 Medline TA: J Pediatr Psychol Country: United States |
Other Details:
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Languages: eng Pagination: 379-88 Citation Subset: IM |
Affiliation:
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Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada. hopewalker@psych.ubc.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic beta-Agonists / therapeutic use Asthma / drug therapy*, immunology*, physiopathology, psychology* Biological Markers / blood* Bronchodilator Agents / therapeutic use Child Cytokines / blood Eosinophils Female Health Knowledge, Attitudes, Practice* Humans Immunoglobulin E / blood Inflammation / blood, drug therapy Leukocyte Count Male Parents* Quality of Life / psychology Questionnaires Respiratory Function Tests / methods Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Agonists; 0/Biological Markers; 0/Bronchodilator Agents; 0/Cytokines; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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