| The role of aldosterone receptor antagonists in the management of heart failure: An update. | |
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MedLine Citation:
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PMID: 22949344 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aldosterone receptor antagonists (ARAs) spironolactone (Aldactone) and eplerenone (Inspra) have become part of standard medical therapy for heart failure, having shown clinical efficacy in randomized trials in patients with advanced symptomatic systolic heart failure, postinfarction heart failure with cardiac dysfunction, and systolic heart failure with mild symptoms. The benefits include a lower rate of death. Yet to be answered is whether the two drugs are clinically equivalent; another question is whether they may benefit everyone with symptomatic heart failure, including diastolic heart failure. |
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Authors:
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Vijaiganesh Nagarajan; Mohammed Chamsi-Pasha; W H Wilson Tang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cleveland Clinic journal of medicine Volume: 79 ISSN: 1939-2869 ISO Abbreviation: Cleve Clin J Med Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-09-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703441 Medline TA: Cleve Clin J Med Country: United States |
Other Details:
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Languages: eng Pagination: 631-9 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Medicine, J3-4, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; tangw@ccf.org. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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