Document Detail

The role of RBC transfusion in the premature infant.
MedLine Citation:
PMID:  6206718     Owner:  NLM     Status:  MEDLINE    
Fifty-six premature infants with a mean gestational age at birth of 30 weeks were randomly assigned to a transfusion group, for whom the hemoglobin level was kept above 10.0 g/dL, and a nontransfusion group, who were transfused only for specific clinical indications. The groups were followed up longitudinally with weekly determinations of reticulocyte count, the partial pressure of oxygen at which 50% of hemoglobin is saturated, and hemoglobin F percentage, as well as weight gain, length of stay, hospital cost, and frequency and severity of apnea. At birth, there was no significant difference in birth weight, gestational age, and hemoglobin level between the two groups. At discharge, laboratory differences were noted between the two groups, but there was no clinical difference. We found no clinical advantage to the use of "booster" RBC transfusions in growing premature infants.
J P Blank; T G Sheagren; J Vajaria; H H Mangurten; R S Benawra; B L Puppala
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  138     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-09-26     Completed Date:  1984-09-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  831-3     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Birth Weight
Blood Transfusion*
Body Weight
Erythrocyte Count
Erythrocyte Transfusion*
Fetal Hemoglobin / analysis
Follow-Up Studies
Gestational Age
Hospitalization / economics
Infant, Newborn
Infant, Premature*
Intensive Care Units, Neonatal
Length of Stay
Random Allocation
Reg. No./Substance:
9034-63-3/Fetal Hemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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