| The role of the National Institute on Drug Abuse in the development of naltrexone. | |
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MedLine Citation:
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PMID: 6088469 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Naltrexone was administered to 114 opiate-addicted business executives and 15 opiate-addicted physicians within a highly structured abstinence-oriented aftercare program following an inpatient detoxification program that used clonidine. The majority of patients successfully completed 6 months of naltrexone treatment without missed visits or drug-positive urines, and were still opiate-free at 12- to 18-months follow-up. The most successful outcomes were achieved by those who had entered treatment with unequivocal job jeopardy. Our findings suggest that naltrexone can be an extremely useful adjunct in the treatment of opiate addiction when administered to employed, motivated patients within a highly structured therapeutic program. |
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Authors:
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H M Ginzburg; W J Glass |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The Journal of clinical psychiatry Volume: 45 ISSN: 0160-6689 ISO Abbreviation: J Clin Psychiatry Publication Date: 1984 Sep |
Date Detail:
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Created Date: 1984-10-22 Completed Date: 1984-10-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7801243 Medline TA: J Clin Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 4-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aftercare Animals Carcinogens Clinical Trials as Topic Clonidine / therapeutic use Drug Administration Schedule Drug Evaluation Drug Evaluation, Preclinical Drug and Narcotic Control Female Humans Male Mice Motivation Naloxone / analogs & derivatives* Naltrexone / therapeutic use*, toxicity Opioid-Related Disorders / drug therapy, rehabilitation* Patient Compliance Rats United States United States Substance Abuse and Mental Health Services Administration* |
| Chemical | |
Reg. No./Substance:
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0/Carcinogens; 16590-41-3/Naltrexone; 4205-90-7/Clonidine; 465-65-6/Naloxone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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